Advertisements

Advertisements

Plasma Proteins Separation, Properties & Origin

Blood Plasma Proteins Presentation / Essay for Medical Biology Students & Kids

SEPARATION OF PLASMA PROTEINS

The plasma proteins can be separated by the following methods.

1. PRECIPITATION METHOD

2. SALTING OUT METHOD

3. ELECTROPHORETIC METHOD

4. COHN'S FRACTIONAL PRECIPITATION METHOD

5. ULTRA CENTRIFUGATION METHOD

6 IMMUNOELECTROPHORETIC METHOD


PROPERTIES OF PLASMA PROTEINS 

The following are the properties of plasma proteins. 


1. MOLECULAR WEIGHT 

The molecular weight of albumin : 69,000

The molecular weight of globulin: 1,56,000

The molecular weight of fibrinogen : 4,00,000

Thus, the molecular weight of fibrinogen is greater than that of other two proteins.


2. ONCOTIC PRESSURE 


The plasma proteins are responsible for the oncotic or osmotic pressure in the blood. The osmotic pressure exerted by proteins in the plasma is called colloidal, osmotic pressure. Normally, it is about 25 mm Hg. Albumin plays a major role in exerting oncotic pressure. 


3. SPECIFIC GRAVITY 

The specific gravity of the plasma proteins is 1.026. 


4. BUFFER ACTION 

The acceptance of hydrogen ions is called buffer action. The plasma proteins have 1/6 of total buttering action of the blood. 


ORIGIN OF PLASMA PROTEINS 


IN EMBRYO 

In embryonic stage, the plasma proteins are synthesized by the mesenchyme cells. In embryo, the albumin synthesized first and other proteins are synthesized later. 


IN ADULTS 

In adults, the plasma proteins are synthesized mostly from the reticuloendothelial cells of liver. The plasma proteins are also synthesized from spleen , bone marrow and disintegrating blood cells and general tissue cells. Gamma globulin is synthesized from B lymphocytes.


Download Note on Plasma Proteins Functions

No comments:

Post a Comment

Advertisements