Advertisements

Advertisements

What are Functions of Plasma Proteins

Blood Plasma Proteins 10 Important Functions – Coagulation, Defense, Transportation, Blood Pressure Maintenance, Viscosity & Acid Base Balance in a human body 

FUNCTIONS OF PLASMA PROTEINS 

The plasma proteins are very essential for the body. The following are the various functions of the plasma protein 

1. ROLE IN COAGULATION OF BLOOD 

Fibrinogen is essential for the coagulation of blood. During coagulation of blood, the fibrinogen is converted into fibrin. 


2. ROLE IN DEFENSE MECHANISM OF BODY 

The gamma globulins play an important role in the defence mechanism of the body by acting as antibodies (immue substances). These protein are also called immunoglobulins. The antibodies react with antigens of various microorganisms, which cause diseases like diphtheria, typhoid, streptococcal infections, mumps, influenza ,measles, hepatitis, rubella, poliomyelitis, etc.



3. ROLE IN TRANSPORT MECHANISM 

Plasma proteins are essential for the transport of various substances in the blood. Albumin, alpha globulin and beta globulin are responsible for the transport of the harmone, enzymes and respiratory gases, particularly carbondioxide,. The alpha and beta globulins play an important role in the transport of metals in the blood.

4. ROLE IN MAINTENANCE OF PRESSURE IN BLOOD

Because of their large size, the plasma proteins cannot pass through the capillary membrane easily and remain in the blood. In the blood these proteins exert the colloidal oncotic pressure.The oncotic pressure exerted by the plasma proteins is about 25 mm Hg. In this way, the plasma proteins play an important role in the maintainence of oncotic pressure of blood.

Since the concentration of albumin is more than the other plasma proteins, it exerts maximum pressure. Globulin is the next and fibrinogen exerts least pressure.

Importance of Oncotic Pressure - Starling's Hypothesis

Oncotic pressure exerted by the plasma proteins js involved in the exchange of various substances between blood and the cells through capillary membrane. Accord­ing to Starling's hypothesis, the net filtration through capillary membrane is proportional to the hydrostatic pressure difference across the membrane minus the oncotic pressure difference. 


5. ROLE IN REGULATION OF ACID BASE BALANCE 

Plasma proteins, particularly the albumin, play an important role in regulating the acid base balance in the blood. This is because of the virtue of their buffering action 


6. ROLE IN VISCOSITY OF BLOOD 

The plasma proteins provide viscosity to the blood, which is important to maintain the blood pressure. Albumin provides maximum viscosity than the other plasma proteins. 


7. ROLE IN ERYTHROCYTE 

SEDIMENTATION RATE (ESR)

Globulin and fibrinogen of the plasma accelerate the tendency of rouleaux formation by the red blood cells. Rouleaux formation is responsible for ESR, which is an important diagnostic and prognostic tool for the clinicians .The tendency of red blood corpuscles to pile up one above another is called rouleaux formation. 


8. ROLE IN SUSPENSION STABILITY OF RED BLOOD CELLS 

During circulation, the red blood cells remain suspended uniformly in the blood. This property of the red blood cells is called the suspension stability. Globulin and fibrinogen help in the suspension stability of the red blood cells. 


9. ROLE IN PRODUCTION OF TREPHONE SUBSTANCES 

Trephone substances are necessary for nourishment of tissue cells in culture. These substances are produced by leukocytes from the plasma proteins. 


10. ROLE AS RESERVE PROTEINS 

During the conditions like fasting, inadequate food intake or inadequate protein intake, the plasma proteins are utilized by the body tissues. Because of this, the plasma proteins are called the reserve proteins.


Download Presentation on Plasma Proteins Functions

2 comments:

Advertisements