Cobalt as Mineral – Rich Food Sources, Functions, Deficiency & Daily Requirements for Children, Men & Women

Presentation Notes on Cobalt (Co) Vegetarian & Non Vegetarian Food Sources, Recommended Dietary Allowance, Cobalt deficiency disorders, Role in Human Body with Treatment & Toxicity in word / .doc / .ppt format

Cobalt:-

Cobalt is a constituent of vitamin B12. The total body content of cobalt is 1.1 mg. It is readily absorbed from the small intestine.

Daily requirement:

• Though the average intake of cobalt is 0.3 mg per day, the daily requirement has not yet been established.

Sources:

• Figs
• cabbage
• lettuce
• spinach
• animal products such as liver and kidneys.

Functions:

• It is a component of vitamin B12 which contains 4% of the element. It is necessary for Hb formation. It plays an analogous role to copper in ferroxidase and iron in Hb.
• Cobalt may substitute for manganese as an activator of enzymes. It is a specific activator of the enzyme, glycylglycine dipeptidase. It also activates enzymes such as phosphotransferases and lyases.
• It causes an increase in the number of RBCs.
• Cobalt induces polycythemia by increasing formation or inhibiting destruction of erythropoietin, the stimulating hormone secreted by kidney. This leads to the development of macrocytic anaemia.

Excretion:

• 0.26 mg/day is excreted in urine.

Toxicity:

• Cobalt it added during processing of beer as a foam stabilizer. Congestive heart failure from cardiomyopathy has been reported in individuals who have consumed large quantities of beer.

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